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Psychedelics are powerful substances that should always be approached with respect, intention, reverence, and education. When used in the right set and setting, they can be among the most meaningful and spiritual experiences in a person’s life.
But these journeys also carry risks and can result in tragedy if certain safety precautions are ignored. The strength of your experience depends on the substance, dosage, mindset, environment, and how prepared/supported you are.
If you’re considering working with psychedelics:
Psychedelics can be unpredictable. Healthy or experienced individuals can also have very challenging trips.
Personal Safety Consultation with expert support in reviewing your product, dosage, set, and setting is available.
Explore the resources listed below to prepare yourself and understand both the risks and benefits of consuming psychedelics.


This screening form will help inform you of potential risks associated with you and your family's medical history.

This questionnaire will help you track and understand the intensity of your experience. Record your score and the dosage consumed with journal entries to help you discover your preferred level of altered consciousness.

Certain pharmaceutical medications can be deadly when combined with psychedelics. Others may significantly increase or decrease the effects, even if you have stopped taking the medicine for months.
This resource specifically addresses psychedelic interactions with antidepressants. Be sure to consult your medical provider to ensure there
Certain pharmaceutical medications can be deadly when combined with psychedelics. Others may significantly increase or decrease the effects, even if you have stopped taking the medicine for months.
This resource specifically addresses psychedelic interactions with antidepressants. Be sure to consult your medical provider to ensure there are no harmful interactions with other medications you may be taking.

This search engine maintained by The United States Library of Medicine can be used to research peer-reviewed journal articles about psychedelics.

A small non-commercial organization that operates in the controversial and politically challenging niche of trying to provide accurate, specific, and responsible information about how psychoactives are used in the United States and around the world. They have been a trusted source of information for 30 years.

Affordable potency testing and other harm reduction/support services for the personal use of natural medicine and cannabis.

This community gathering is the last Sunday of every month in Denver, CO and offers a safe space to explore the incredibly synergistic effects of psilocybin and sound baths.
This Colorado Senate Bill explains personal use freedoms relating to natural medicine for those over the age of 21. It includes certain requirements for those providing harm reduction/support services used concurrently with the sharing of natural medicine and natural medicine products.
Call or text 623-473-7433 everyday from 11 am - 11 pm pacific time for support during or after psychedelic experiences. Totally free. Always confidential.
The Department of Revenue (DOR) licenses and regulates natural medicine healing centers, cultivations, manufacturers, testing facilities, and their owners and employees.
The Department of Regulatory Agencies (DORA) licenses and regulates facilitators of natural medicine services.
The Center for Medicinal Mindfulness has created an in-depth journaling guide designed to help individuals process and integrate the insights from their psychedelic experiences. This comprehensive workbook offers structured prompts, reflective exercises, and practical tools for emotional, mental, and spiritual integration. We share this w
The Center for Medicinal Mindfulness has created an in-depth journaling guide designed to help individuals process and integrate the insights from their psychedelic experiences. This comprehensive workbook offers structured prompts, reflective exercises, and practical tools for emotional, mental, and spiritual integration. We share this workbook with our clients and friends for post-journey support. Whether you're seeking clarity, grounding, or long-term transformation, this resource provides supportive guidance to carry the wisdom of your journey into everyday life.
Retreats, intuitive guidance, and energy healing with practical techniques and strategies for self-empowerment.
This bona fide harm reduction/support service used concurrently with the sharing of natural medicine or natural medicine product is for the personal use of those twenty-one (21) years of age or older and understand that SOUL-N-SCIENCE is not licensed by the State of Colorado to conduct testing, cultivation, manufacturing, nor is a licensed facilitator pursuant to article 170 of title 12.
